Comparison of clinical outcomes of conventional hemodialysis and online hemodiafiltration

Background: Several studies have suggested that online hemodiafiltration (OL-HDF) may reduce the risk of mortality and improve quality life these patients compared with standard hemodialysis. Methods: Forty stable out on dialysis (20 hemodialysis 20 hemodiafiltration) above age 18 years vintage more than 3 months were followed up for months. Clinical, biochemical parameters along SF-36 score at baseline after follow assessed. Results: At months, statistically significant difference was found between (HD) OL- HDF groups in erythropoietin dose (p=0.047), urea reduction ratio (p=0.016), Kt/V (p=0.005), hemoglobin (p=0.043), serum albumin (p=0.002), phosphorus (p=0.024), parathyroid hormone (p=0.007), potassium β2 microglobulin high sensitive c-reactive protein (p=0.037), bicarbonate levels (p=0.022). We intradialytic complications namely hypotension, muscle cramps, simultaneous hypotension cramps stoppage dialysis. In terms mortality, not (p=0.052). Conclusions: Patients having better HD. Better solute clearance, anemia control, improved nutritional Mineral bone disorder seen OL-HDF. Less during The rate HD group significant.